Multiphysical phenomenon of air bubble growth in polydimethylsiloxane channel corners under microfluidic negative pressure-driven flow
Abstract(#br)The air bubbles can be used in a controlled fashion for multiphase microfluidics but also frequently plague microfluidic devices when unrestrained. However the phenomenon of the undesired air bubble growth in microfluidic channels has not been systemically studied yet. Based on a coupled-physics model, herein we try to explain the process of unwanted air bubble growth during microfluidic negative pressure-driven flow in polydimethylsiloxane (PDMS) channel corners with both theoretical and experimental approaches.